Resident Evil 3 Producer, Peter Fabiano, confirmed that the 4v1 asymmetrical Resistance is “basically set in Raccoon City with scenarios that make it impossible to fit in the actual timeline”, though players can expect to “see familiar enemies and characters like Mastermind.”
Fabiano also explained why Capcom decided to bundle Resistance with RE3 itself.
“You’ll remember that the Japanese subtitle for RE3 was Last Escape,” Fabiano continued. “Both of these titles have characters that are trying to escape somewhere or something, so thematically it made sense. We also wanted to take up the challenge of building out an online game set in the RE universe.”